Over 200 baldness-linked genetic markers uncovered

Bald man

Bald man

Numerous identified genes are related to hair structure and development. Thus although these findings do not help us exactly predict hair loss, they are a step closer to this worthy goal.

Research from the United Kingdom -based University of Edinburgh found that more than 250 genetic conditions were responsible for male pattern baldness after analyzing more than 52,000 subjects aged 40-69.

The study's other lead author, Dr. David Hill, notes that the study did not collect data on the age of baldness onset, but only on hair loss pattern. These new findings could be used to predict the chances that a man will suffer from severe hair loss.

Scientists have identified more than 200 new genetic regions linked with male pattern baldness, which could be used to predict a man's chances of severe hair loss.

Two-thirds of American men will experience some degree of male pattern baldness by 35, and the condition is responsible for 95 percent of all hair loss in men. With the results, the researchers hope to identify people within the population at risk for hair loss. One of the genes on the X chromosome - the gene for the androgen receptor, which binds to the hormone testosterone - was strongly linked with severe hair loss.

They identified 287 genetic regions linked to the condition.

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Scientists analyzed the genomic and health data of more than 52,000 men enrolled in the UK Biobank - an global health resource offering health information on more than 500,000 individuals.

Earlier studies have pointed to eight predictable markers of hair loss in men.

"We are still a long way from making an accurate prediction for an individual's hair loss pattern", principal study investigator Riccardo Marioni, of the University of Edinburgh, said in a statement from the Public Library of Science posted on Medical Xpress.

After this study, the researchers developed a formula based on the results.

Previously genes have been found to link baldness with prostate cancer and cardiovascular disease.

"It was interesting to find that numerous genetics signals for male pattern baldness came from the X chromosome, which men inherit from their mothers". More to the point for those anxious about it is the second half of this sentence: "The results of this study might help identify those at greatest risk of hair loss, and also potential genetic targets for intervention", says a study co-author, per NBC News.

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